3. Role des metabolites secondaires dans les symbioses

It is now well-accepted that most organisms have an associated symbiotic microbiome, and that this microbiome interacts with this host. Since these interactions depend on a communication of a chemmical nature, undestanding the origin and role of these molecules in these symbiosis is one of the goals in this axis

Some recently publications in this topic include:

• Grellier N, Suzuki MT, Brot L, Rodrigues AMS, Humbert L, Escoubeyrou K, Rainteau D, Grill J-P, Lami R, Seksik P (2022) Impact of IBD-Associated Dysbiosis on Bacterial Quorum Sensing Mediated by Acyl-Homoserine Lactone in Human Gut Microbiota. International journal of molecular sciences 23
• Barthelemy M, Elie N, Genta-Jouve G, Stien D, Touboul D, Eparvier V (2021) Identification of Antagonistic Compounds between the Palm Tree Xylariale Endophytic Fungi and the Phytopathogen Fusarium oxysporum. Journal of Agricultural and Food Chem 69:10893-10906
• Pellissier L, Leoni S, Marcourt L, Queiroz EF, Lecoultre N, Quiros-Guerrero LM, Barthelemy M, Eparvier V, Chave J, Stien D, Gindro K, Perron K, Wolfender JL (2021) Characterization of Pseudomonas aeruginosa Quorum Sensing Inhibitors from the Endophyte Lasiodiplodia venezuelensis and Evaluation of Their Antivirulence Effects by Metabolomics. Microorganisms 9:24