4. Interactions bactériennes : Biofilms, Quorum-Sensing Fouling

Biofilms are complex microbial associations that develop in a wide variety of environments. They colonize all natural or artificial surfaces and are essential to the proper functioning of ecosystems and organisms. However, these structures can also prove harmful in a variety of contexts: as reservoirs for pathogenic organisms, as preferred environments for the acquisition of antibiotic resistance, as a means of obstructing pipes through growth, as a means of accelerating corrosion processes, and so on. Research into biofilms at LBBM has taken off in a particularly significant way, in line with the tools developed for the study of quorum sensing a key mechanism in biofilm growth.

Some recent publications from this activity include:

• Romani M, Warscheid T, Nicole L, Marcon L, Di Martino P, Suzuki MT, Lebaron P, Lami R (2022) Current and future chemical treatments to fight biodeterioration of outdoor building materials and associated biofilms: Moving away from ecotoxic and towards efficient, sustainable solutions. Sci Total Environ 802:21
• Rodrigues AMS, Lami R, Escoubeyrou K, Intertaglia L, Mazurek C, Doberva M, Perez-Ferrer P, Stien D (2022) Straightforward N-Acyl Homoserine Lactone Discovery and Annotation by LC-MS/MS-based Molecular Networking. J Proteome Res 21:635-642
• Romani M, Adouane E, Carrion C, Veckerle C, Boeuf D, Fernandez F, Lefevre M, Intertaglia L,Rodrigues AMS, Lebaron P, Lami R (2021) Diversity and activities of pioneer bacteria, algae, and fungi colonizing ceramic roof tiles during the first year of outdoor exposure. Int Biodeterior Biodegrad 162:14
• Urvoy M, Lami R, Dreanno C, Daude D, Rodrigues AMS, Gourmelon M, L'Helguen S, Labry C (2020) Quorum sensing disruption regulates hydrolytic enzyme and biofilm production in estuarine bacteria. Environ. Microbiol.:18